Axl as a mediator of cellular growth and survival

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Axl as a mediator of cellular growth and survival

The control of cellular growth and proliferation is key to the maintenance of homeostasis. Survival, proliferation, and arrest are regulated, in part, by Growth Arrest Specific 6 (Gas6) through binding to members of the TAM receptor tyrosine kinase family. Activation of the TAM receptors leads to downstream signaling through common kinases, but the exact mechanism within each cellular context v...

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ژورنال

عنوان ژورنال: Oncotarget

سال: 2014

ISSN: 1949-2553

DOI: 10.18632/oncotarget.2422